JTD, I am looking at 65gr Sierra spitzer soft points for the .223, as for the .22-250 and .243WSSM, I haven decided on anything yet. From everything I read and been told about those 2 rounds, they are mostly for varmints and coyotes and I hunt hogs and deer for meat, don't know if I would use either unless I was going to go a head or neck shot. I may end up selling them both.