From a guy that I consider a guru of reloading, early on he said if you really want to prep your brass for the most uniform shooting that besides having it sized he also recommended drilling the flash hole so they are all the same and running a carbide uniformer for the primer pocket. I get a lot of brass coming out of the cases on the flash hole drill/shaping and on the uniformer it depends on the case but usually at least the carbon is coming off. These are .243 cases in the pictures.
Does it make a difference, don't know as I do that will all my rifle centerfire brass.
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