I've arrived at a few loads that I'm comfortable with for our SE GA deer and hogs.
In general about 500ftlbs @ 100 yards is plenty around here on the deer.
Listed below are chronographed loads with various barrels, some of you may find the velocities interesting, others will see it mostly does fit the 25fps drop per inch from 16" to 10" and then 50fps per inch afterwards.
I have found a favorite for the 16" and 7 1/2" AR barrels but nothing really stands out yet in the 11 1/2" single shot pistol.
135gr Sierra HP #2124 with 20.0gr of AA1680 (favorite in 16")
16" barrel @ 1940fps with 850ftlbs @ 100 yards
11 1/2" barrel @ 1800fps
7 1/2" barrel @ 1533fps
150gr Hornady RN #3035 with 19.0gr of AA1680 (7 1/2" favorite)
16" barrel @ 1870fps
11 1/2" barrel @ 1730fps
7 1/2" barrel @ 1483fps with 492ftlbs @ 100 yards
166gr cast powder coated Lee c309-160-R with 18.0gr AA2230
16" barrel @ 1500fps with 605ftlbs @ 100 yards
11 1/2" barrel @ 1371fps
166gr cast powder coated Lee c309-160-R with 18.5gr of AA2230
7 1/2" barrel @ 1315fps
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