When there were shortages of supplies I bought up whatever powder I ran across. I use H110, Lil Gun, and CFE BLK in my .300 Blackout. All work fine for me. Believe my brother in law said that H110 is a powder he saw load date for the .450 BM. I haven't yet jumped into that realm yet. I have the brass, scope, and plenty of powder but not rifle yet. Good luck with whatever you do.