I've shot one deer with them, my son-in-law one deer and my Dad 2 deer with them with one of my guns. I had a pretty good load but have moved on to a different caliber. I shot a .270 with it and lost the deer and my gun was shooting incredibly accurate. Still not sure what happened as I had a good look, good shot and it would shoot within 3/4" of center at 200yds. I've switched to Accubonds and Federal Trophy bullets. With the .243 I don't think any of the 4 deer got more than 20' after being shot.